Which weapons are the best suited for use in Mass Effect 3?ĭisclaimer: that most DLC weapons will not be included in this list. So, in this article, we will explore just that. Because when push comes to shove, the most optimized loadout will keep the squishiest Adept alive just as long as the beefiest Vanguard. In the Mass Effect games, weapons have always been an essential part of gameplay, even if certain classes don’t call for them. Mass Effect 3 Best Weapons (And How To Get Them)